Identifying Reliable Diagnostic/Predictive Biomarkers for Rheumatoid Arthritis
نویسندگان
چکیده
منابع مشابه
Biomarkers in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory autoim-mune disease that leads to severe joint destruction with deformity and irremediable disability. Early diagnosis of RA and timely initiation of treatments (synthetic and/or biological disease modifying antirheumatic drugs) are both instrumental to limit joint damage and optimize the functional outcome of patients, according to the well-k...
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Effective treatment of rheumatoid arthritis (RA) has been hampered by the heterogeneity of the disease. Although early intervention can result in disease remission, it requires early diagnosis - and current diagnostic tests are not sufficiently accurate or sensitive in the early stages of RA. As a result, RA is typically diagnosed only once damage to the joints has already begun, a time at whic...
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Rheumatoid arthritis (RA) is a common autoimmune disease affecting around 1% of the population. Although major advances have been made in the treatment of RA, still relatively little is known on disease pathogenesis and aetiology. From treatment studies it has become clear that treating patients early in their disease course will provide the best results. However, especially in the early phase ...
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UNLABELLED Rheumatoid arthritis (RA) is a chronic inflammatory disease with autoimmune pathogenesis. It affects mainly small joints (of the hands and feet) and has many systemic manifestations. Studying biomarkers in rheumatology intensely appeared from the need to understand the mechanisms underlying some rheumatic diseases. Discovering new biomarkers with key roles in various stages of evolut...
متن کاملCytokines as Biomarkers in Rheumatoid Arthritis
RA is a complex disease that develops as a series of events often referred to as disease continuum. RA would benefit from novel biomarker development for diagnosis where new biomarkers are still needed (even if progresses have been made with the inclusion of ACPA into the ACR/EULAR 2010 diagnostic criteria) and for prognostic notably in at risk of evolution patients with autoantibody-positive a...
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ژورنال
عنوان ژورنال: Biomarker Insights
سال: 2018
ISSN: 1177-2719,1177-2719
DOI: 10.1177/1177271918801005